beijinganbiqishengwukejiyouxiangongsidehuahewu（huahewu、yingguangjituan、tongweisu、danbai）ouliankangticexufuwu，nenggoutigongquanxuliefugaidekangticexufuwu。

huahewuouliankangti，youchengkangti-yaowuoulianhuahewu。qizhongyigehuoduogeyaowubufentongguogongjiafangshilianjiedaokangtishang，kangtijinerjieheqibadianshouti，huozhejieheyizhonghuoduozhongzhongliuxiangguankangyuanhuoxibaobiaomianshouti。kangzhongliukangtitongguohuaxuexiushiyuxiaoyingfenzioulian，zheixieoulianwujiyouteyixingshibiezhongliukangyuandenengli，yebaoliulexiaoyingfenzishashangzhongliuxibaodeduxing，zhusheyuzhongliuhuanzhetinei，kedingxiangdijujidaozhongliubuwei，xuanzexingshashangzhongliuxibao。

图1. ADCs(antibody drug conjugates)结构示意图（Chen 2014）

muqianchangyongdekangtirengyishuyuandankangjuduo，xiaoyingfenzizhuyaoxuanyongdudanbaidanlian、fangshexinghesuhekangaiyaowudeng。kangtioulianwuzaizhongliudongwuzhongxianshichulekangzhongliuxiaoguo，kejianqingxiaoyingfenzidedufuzuoyong，yanzhangdongwushouming。zairenleizhongliuzhiliaozhong，kangtioulianwuduibaixuebinghelinbaliuyeyouyidingliaoxiao，danyinshejihamafanying，kenenghuiyingxiangyixiezhongliuzhiliaoxiaoguo。zhibeikangzhongliudekangtiyuxiaoyingfenzi(huahewu、yingguangjituan、tongweisu、danbai)oulianwu，liyongkangtiteyixingshibiezhongliukangyuanzuoyong，shixiaoyingfenziyouxiaodidaodazhongliubuwei，xuanzexingshashangzhongliuxibao。

beijinganbiqishengwukejiyouxiangongsikeyigenjukehuyaoqiu，tigongdankelongkangticexufuwu，duiyubutongwuzhong、tongxingkangtihuotongzhongyixingkangtidecexu。muqian，duiyuhenduoouliankangti（ruapc, pe, alexa and fitc），youyuranliaogongjiajiehedeyuanyin，haibunengjinxingshifenwanzhengqiezhunquedexulieceding。