renkangtihuorenyuanhuakangtideshengchanduihenduojibingdezhiliaoyiyinqileyuelaiyueduodeguanzhu。xianzai，beijinganbiqishengwukejiyouxiangongsikeyiweinintigongxinxingrenkangtihuorenyuanhuakangticexufuwu。womenliyongniaoqiangfayukangtishujukuxiangjiehedejishu“database assisted shotgun sequencing”（dass），dajianlekangticexupingtai。

renyuanhuakangtilaiyuanyufeirenleiwuzhong，tongguoxiushizengjiaqiyurentineitianrankangtidexuliexiangsixing。renyuanhuaguochengduiyuzaifeirenleimianyixitongzhongshengchanteyixingkangtishishifenbiyaode。dankangjishujingguo35niandefazhan，jinglishuyuankangti、qianhekangti、renyuanhuakangtihequanrenyuankangtisigejieduan（ruxiatusuoshi）。renyuanhuakangtiyuqianhekangtibutong，jinguanshengchanqianhekangtishiweilehuodeyurenkangtigengxiangsidekangti，danzheizhongleixingdejiandanqianhetibingbunengbeirenweishirenyuanhuade。tongguocdrs（complementarity-determining regions）shikangtijiehedaomubiaokangyuanshang，renyuanhuakangtidedanbaixuliebenzhishangqishishirenkangtidebianzhong。tongguo“renyuanhua”defangfa，tongchangshiyaokaifayongyurenleidedankelongkangtiyaowu。muqianderenyuanhuakangti，zhuyaoyongyuzhongliu、zishenmianyixingjibinghexinxueguanjibingdezhiliaoyijikangyizhipaichifanyinghekangbingduganrandengfangmian。zaiquanqiudankangshichangzhong，renyuandankangshiqiweilaidefazhanfangxiang，yizaioumeishangshide32gedankangzhong，you9geshiquanrenyuandankang，suizhezhuanjiyinxiaoshuheshijuntijishudechenggongyingyong，quanrenyuandankelongdankangdebizhongjiangzhujianzengda。

huodegaoteyixingheqinhexingderenhuorenyuanhuakangti，duihenduojibingjinxingyouxiaodekangtizhiliaojuyouyuelaiyuezhongyaodezuoyong。beijinganbiqishengwukejiyouxiangongsikeyigenjukehuxuyao，tigongrenkangtihuorenyuanhuakangticexufuwu。