beijinganbiqishengwushuangyingguangsumeibaogaojiyinshiyanxitongcaiyongyinghuochongyingguangsumeihehaishenyingguangsumeizuchengshuangyingguangsumeibaogaojiyinshiyanxitong。shiyanzhong，baogaojiyin（yinghuochongyingguangsumei）huolidegaibian，yujiyinbiaodadetedingshiyantiaojianxiangguan；ershizongjiyin（haishenyingguangsumei）zuoweineiduizhao，shiceshibubeishiyantiaojianbianhuasuoganrao，jianshaoneizaidebianhuayinsusuoxueruodeshiyanzhunquexing，ru，peiyangxibaodeshumuhehuolidechabie，xibaozhuanranheliejiedexiaolvdeng。yinghuochongyingguangsumeihehaishenyingguangsumeiceshidezuhe，tigongleshuangyichuanbaogaojiyinyingyongdelixiangceshixitong。

启动子与转录因子相互作用检测

 zhuanluyinzishiyizhongjuyouteshujiegou、xingshidiaokongjiyinbiaodagongnengdedanbaizhifenzi，yechengweifanshizuoyongyinzi。mouxiezhuanluyinzijinyuqibaqidongzizhongdeteyishunxujiehe，zheixieteyixingdexuliebeichengweishunshiyinzi。zhuanluyinzidednajieheyuheshunshiyinzishixianxianghujiehe，congerduijiyindebiaodaqiyizhihuozengqiangdezuoyong。yingguangsumeibaogaojiyinshiyanshijiancezheileizhuanluyinziheqibaqidongzizhongdeteyishunxujiehedezhongyaoshouduan。

技术流程

启动子与转录因子相互作用检测工作原理
应用领域

• qianzaiqidongzi/qidongzihexinquyujiance；

• qianzaizengqiangzi/yizhizidengdiaokongzihexinyuanjianjiance；

• qidongziqukenengdezhuanluyinzijieheweidianjiance；

• qidongzi/zengqiangziyuzhuanluyinzidexianghuzuoyong；

• bingdu/xibaoxianghuzuoyong；

• yaowudenghuaxueyoudaoyinsuduiqidongzihuoxingdediaojie（yizhihuozengqiang）；

• shexiandengwuliyoudaoyinsuduiqidongzihuoxingdediaojie（yizhihuozengqiang）。

miRNA与3’UTR相互作用检测

beijinganbiqishengwuketigonghanyouyingguangsumeibaogaojiyinderen、dashu、xiaoshude3' utrbabiaokelong，liyongyingguangsumeibaogaoxitongtiwaiyanzhengmirnaqianzaibajiyin。mirnas yubajiyinde3' utrquyuteyijiehehoudiaojiebajiyindebiaoda。dang3' utrbabiaoxulieronghezaiyigeyingguangsumeibaogaojiyinxiayoubingzaitiwaibiaodashi，mirnatongguoyuxiayou3' utrteyijiehecongerdiaojieyingguangsumeidebiaoda。tongguofenxiyingguangsumeidehuoxing，jianjielejiemirnadebabiaodiaokongzuoyongheteyixing。

参考文献
[1] Pan Y, Geng R, Zhou N, et al. TBX20 loss-of-function mutation contributes to double outlet right ventricle[J]. International journal of molecular medicine, 2015, 35(4): 1058-1066.
[2] Sterling L, Walter M, Ting D, et al. Discovery of functional non-coding conserved regions in the α-synuclein gene locus[J]. F1000Research, 2014, 3.
[3] Xu, R. X., R. Y. Liu, C. M. Wu, Y. S. Zhao, Y. Li, Y. Q. Yao and Y. H. Xu (2015). Xu R X, Liu R Y, Wu C M, et al. DNA damage-induced NF-κB activation in human glioblastoma cells promotes miR-181b expression and cell proliferation[J]. Cellular Physiology and Biochemistry, 2015, 35(3): 913-925.
[4] Cao R, Yu T, Li S, et al. Tu1690 MiR-130b Plays an Oncogenic Role by Repressing PTEN Expression in Esophageal Squamous Cell Carcinoma[J]. Gastroenterology, 2014, 146(5): S-819.

询价及订购

ganxieninxuanzewogongsidejiyinkelongfuwu。ruyourenhexiangguandewenti，qingninlianxiwomendegongzuorenyuan，womenjinkuaiweininjiedahefuwu。