jinnianlaidexinguanyiqingshimrnayimiaojishudedaoqiansuoweiyoudekuaisufazhan，tongshimrnayimiaozaichuanranbingfangzhilingyudezhenduixingqiangheyanfazhouqiduandengyoushiyeyoumugongdu。chuciyiwai，mrnazuoweiyaowuzaizhongliuzhiliaoyijidanbaizhitidailiaofadenglingyuyejuyoujidaqianli。mrnayuanyededaguimoshengchanjuyoutiaozhanxing。anbiqishengwukejiyongyouwanshandezhiligmpshengchanhemrnahechengdegongyiliucheng，zhiliyuweiyiyaogongsi、gongyekehutigonggmpjibiedemrnashengchanfuwu。

服务特色

• gaozhilianggmpjibiedemrnashengchanfuwu。

• linghuokefangdadeshengchanguimo，ketigongconghaokedaobaikejibiedemrna。

• yizhanshifuwu，zhenduichanpinxuqiuduixulieyouhua、jiamaofangshixuanzeheheganxiushidengfangmianjinxinggongyiliuchengdegexinghuadingzhisheji。

• tigonggaoxiaobingjingjidezuizhongjiejuefangan，genjuchanpintezhengcongfanyingzufenhechunhualiuchengshangjinxinggexinghuadiaozheng。

• juyouzhuanyebingjingyanfengfudetuandui、biaozhunjiwanbeidexiangmuguanliliuchenghebaomijizhi。

服务流程

• 质粒GMP生产与线性化

zhilidnashimrnashengchandeqishicailiao，zhilizaitishangbaohanrnajuhemeideteyiqidongzihezuizhongmrnachanwudexuliexinxi。mrnazhibeiqian，zhilixujingguoxianzhixingneiqiemeijinxingxianxinghuachuli，zaijingguoduobucengxihechaolvgongyijinxingchunhua，jiancehegedexianxingdnabiankeyongyuhouxumrnadeshengchan。

womenkegenjunindexuqiujinxingmrnaxulieshejijiyouhua，bingtigonggmpjizhilishengchanhexianxinghuamobanzhibeidecongtoushejiheshengchanfuwu。

• mRNA的体外转录（IVT）制备与纯化

mrnatongguotiwaizhuanlufanyingshengchan，5'duanmaozijiegoudetianjiafangshikefenweiyinrumaozileisiwudeyibufahejiamaomeijiedaodeliangbufa，kegenjunindexuqiuxuanzejiamaofangshibingjinxingmrnashengchan。xiushihegankeyizaicibuyinrumrna，yitigaomrnadewendingxinghuojiangdimianyiyuanxing。mrnadechunhuaxushiyongdaoduobucengxigongyihechaolvgongyi，yiquchufanyingzhongcanliudedna、yan、ntpdengzazhi，zuizhongdedaogaozhiliang、gaochundudemrna。

mrnadeshengchanhechunhualiuchengkegenjunindechanpinjutitezhenghezuizhongxuqiujinxingyouhuaheguimofangda，manzunindexuqiu。tongshi，womenyetigongrubaogaojiyin、crispr-casmeidengjiyinbianjixiangguandexianhuogmpjibiedemrnachanpin，jutichanpinliebiaokelaidianzixun。

• mRNA原液的质量检测

genju《xinxingguanzhuangbingduyufangyongmrnayimiaoyaoxueyanjiujishuzhidaoyuanze（shixing）》he《analytical procedures for mrna vaccine quality - draft guidelines (usp)》，mrnayuanyejiaofuqianxujinxingzhiliangjiance，duimrnadefuchanwu、fanyingcanliuwuyijimrnawanzhengxingdengfangmianjinxingjiance。ninkegenjuxuqiuxuanzebiaozhunhuaqcfuwuhuodingzhihuadeqcfuwu。jutijiancexiangmuruxia：

我们的设施

• gmp mrnashengchanchejianfenwei dna zhibeiqu、mrna zhibeiquhezhikongqu。yangezunxun《qianyanyaowushengchanzhiliangguanlizhinan》、《yaopinshengchanzhiliangguanliguifan》jiwujunzhijifuluzhongdexiangguanyaoqiu。yangefangzhiyuchanpinzhijiefashengjiechudehuanjingwuran、shebeirongqijujiyuanfuliaozhongkenengyinrurnameidewuran。