xinshirna（messenger rna，mrna）shiyidnadeyitiaolianweimobanzhuanluerlaide、xiedaiyichuanxinxidenengzhidaodanbaizhihechengdeyileidanlianhetanghesuan。zaitiwai，tongguojiangdnamoban、rnajuhemeihehegansuansanlinsuanzhi（ntps）yuhanmeihuanchongye、rnaseyizhijidengjieheqilai，jingguotiwaizhuanlu（in vitro transcription，ivt）keyishixiantiwaihechengmrna。tiwaizhuanludemrnayoujigeyoudian：tameiyoujiyinzuzhenghedefengxian，qibianmadedanbaizhizaixibaozhizhongbiaodabuxuyaochuanguohemo，erqieyouziranjiangjietujing，kequebaoqihuoxingshizanshide。ciwai，ivthechengdemrnakeyijinxingshejihexulieyouhua，yitigaofanyixiaolv，bingqiekezaiivtguochengzhongjiaruxiushihegan，ru5-jiajibaogan（5-methylcytidine, m5c）hejianiaogan（pseudouridine，ψ），yitigaofanyixiaolv，shengwuwendingxing，jiangdimianyiyuanxing。suoyouzheixietedianyinfaleduihechengdemrnazaibutonglingyudetansuo，rujiyinbianji、xibaozhongbiancheng、zhenduiaizhenghechuanranbingdemianyiliaofayijizaishengyixuedeng。
anbiqikeyitigongyixiliedemrnachanpin，5’daiyoucap1maozi，3’daiyoupolyawei，daiyou/budaixiushijianji，yimanzunindegezhongxiayouyingyong。pingjiewomenjingliangdeshebei、xianjindejishuhejingyanfengfudeyuangong，anbiqiyouxinxinweinintigongshihui、youzhidemrna chanpin，yimanzunintedingdeyanjiuxuqiu。
