kangtidegaoteyixinghegaoqinheliyouzhuyujianshaoyaowudeshiyongjiliangjiqianzaifuzuoyong。muqianzhuyaocaiyongdiantubian（dingdiantubianhesuijiyoubian）、cdrquzhongzu、liantihuanyijidnazhongzudengshouduantigaokangtihekangyuandeqinheli。anbiqishengwujiyukangyuan-kangtixianghuzuoyongdejiegouxinxikaizhantiwaiqinhelichengshujishu，tongguojisuanjifuzhumonimouanjisuanbeiqudaidekenengxing，yuceanjisuanbeiqudaihouduikangtijiegoujiyubakangyuanjiehedeyingxiang，bingtongguoshijuntizhanshihuoxibaobiaomianzhanshijishushaixuanchujuyougaoqinhelidekangti。

技术流程

① 设计突变

a.suijitubian：error-prone pcr& dna-shuffling

b.jisuanjifuzhusheji，dingdiantubian：kangtikebianqufvjiegoumoni、kangyuanyukangtikebianquzuoyongfuhewujiegoumoni、kangtiguanjiananjisuanfenxijitubiansheji

②筛选和亲和力测定

liyongshijuntizhanshihuoxibaozhanshijishu，goujiankangtitubianku，shaixuanchugaoqinhelikangti，liyongbiacore/fortebiopingtaicedingkangyuan、kangtiqinheli，bingduishaixuanchudekangtijinxingcexu。

服务内容

• kangticexu、xuliefenxijijiegoushengwuxuefenxi

• 计算机辅助抗体设计

• shijuntishaixuanjiqinheliyanzheng

• 多肽的亲和力成熟

技术优势

• xiangmujingyan：yiwanchengkangtirenyuanhuajiqinhelichengshuxiangmuduoxiang，duogejinggaizaokangtichuyulinchuangyanjiujieduan。

• qinheliketigaoshubeiyishang，tigaozhinmhuozhepmjibie。

• liyongshengwuxinxixuehejiegoushengwuxuedeshouduan，jisuanjifuzhushejikangtidegaizao。

• caiyongtubianjishu，goujiandekangtitubiankukurongzengjia。

技术平台

kangticexu、jiegoushengwuxuefenxi、shijuntizhanshixitong、xibaozhanshixitong、danbaibiaodachunhuaxitong、biacore/fortebioceshipingtai、wendingxibaoxigoujian