waixianzizucexushiliyongxuliebuhuojishujiangquanjiyinzuwaixianziquyudnabuhuobingfujizhihou，tongguogaotongliangcexu，faxianyudanbaizhigongnengbianyixiangguanyichuantubiandejishushouduan。xiangbiyuquanjiyinzucexu，waixianzizucexugengjingjigaoxiao，duiyanjiuyizhidesnp、indeldengjuyoujiaodadeyoushi。
zairenleijiyinzhongdayueyou180,000waixianzi，jinzhanrenleijiyinzude1%-2%，danquebaohanduoda85%jibingxiangguandejiyintubian。renwaixianzizucexukeyiyouxiaodiyanjiuyujibing、zhongqunjinhuaxiangguandechangjianyichuanbianyihexiyouyichuanbianyi。bingtongguojiehedaliangdewaixianzigonggongshujukuwajuefenxibianyijiegouzhijiandeguanlianhezhibingjili。
anbiqideshengwuxinxituanduiweinindewaixianzizucexuxiangmutigongyizhanshidejishufuwu，genjunindeyanjiuxuqiu，liyonggaotongliangcexujishu，weinintuichuwanzhengdejiejuefangan，xiezhuninyiqitansuoshengwuaomi。
我们的优势
xianjindecexupingtai：biaozhunhuadeshiyanliuchengyijixianjindegaotongliangcexupingtai
gaotongliang、gaozhiliangcexu：shiyanzhouqiduan、xiaolvgao、chengbendi、zhiliangkekao
biaozhunhuadefenxiliucheng：zhuanyedeshengwuxinxituanduiyijifenxifuwutixi，weinintigongbiaozhunfenxi、gaojifenxiyijidingzhihuafenxi
fengfudewaixianzizucexujifenxijingyan：zhuanyedecexujishurenyuanxiezhushejishiyanfangan、jiejueshiyanwentibingfenxishiyanjieguo
dingzhihuadewaixianzizucexufangan：kegenjushijixuqiuzhidinggexinghuadewaixianzizucexufangan
技术流程
数据分析
样本要求
| 样本类型 | 总量 | 浓度 | OD260/OD280 |
| 哺乳动物血液 | >2ml | ||
| 基因组DNA | >6μg | ≥50ng/μl | 1.8-2.2 |
技术参数
| 测序平台 | 测序策略 | 数据量 | 运转周期 |
| HiSeq Nextseq 500 Ion Proton | PE150 | 根据具体项目情况而定，不低于合同约定的数据量 | 35个工作日 |
询价及订购
ganxieninxuanzeanbiqidequanwaixianzizucexufuwu。ruyourenhexiangguandewenti，qingninlianxiwomendegongzuorenyuan，womenjikeweininjiedahefuwu。
参考文献
caburet s, arboleda v a, llano e, et al. mutant cohesin in premature ovarian failure [j]. new england journal of medicine, 2014, 370(10): 943-949.
guo g, sun x, chen c, et al. whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation [j]. nature genetics, 2013, 45(12): 1459-1463.
jin z b, huang x f, lv j n, et al. slc7a14 linked to autosomal recessive retinitis pigmentosa [j]. nature communications, 2014, 5.
